Evolving Approaches to Care for Those in Harm's Way

Evolving health care systems and approaches to maintenance of certification.

Balancing benefits and harms in health care.

Editor—The theme issue on balancing benefits and harms in health care highlighted the need to create better systems to detect and share information about adverse events associated with newly licensed drugs or drugs used off licence or for indications not supported by evidence from clinical trials. 2 3 A new project, CICERO (www.pacehealthsystems.com/ cicero.html), proposes to create a global on...

Coming all the way home: integrative community care for those who serve.

This project describes the programming and evaluation of Coming Home Project (CHP) retreats that address the mental, emotional, spiritual, and relationship challenges experienced by those affected by military service and deployments. Three types of retreats held for veterans, service members and their families, as well as professional service providers, were evaluated. Original program-evaluati...

Learning to care for those who can't be cured.

Is yeast on its way to evolving tRNA editing?

In human mitochondria, genes for tRNA(Tyr) and tRNA(Cys) overlap by a single nucleotide. From polycistronic precursors, a 3'-truncated upstream tRNA(Tyr) is released, missing the overlapping position. A subsequent editing reaction restores this position. Similar mitochondrial tRNA gene overlaps exist in all metazoans, but not in organisms such as yeast or Escherichia coli. Therefore, we asked w...